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Description

A subsample of EVs was diluted 1:1000 in sterile PBS to a final volume of 1 mL

At the molecular level, they modulate inflammation-related gene expression by altering membrane phospholipid composition, disrupting lipid raft integrity, inhibiting nuclear factor kappa B (NF-B), and activating PPAR- , thereby promoting anti-inflammatory mediators and suppressing inflammation (18)